• Cooperative supramolecular polymerizations from synthetic macromolecules and nanoparticles
• Folding cooperativity in large, complex macromolecules bearing synthetic polypeptides and the synthesis of macromolecular channels
• Multicatalytic enzyme-polymer assemblies and their applications in effective biomass conversion
• Artificial regulation of protein activities through the formation of cyclic protein-polymer structures

Publications

H. Duan, T. Yang, W. Sklyar, B. Chen, Y. Chen, L. A. Hanson, S. Sun, Y. Lin, and J. He, “Phenylacetylene-Terminated Poly(Ethylene Glycol) as Ligands for Colloidal Noble Metal Nanoparticles: a New Tool for ‘Grafting to’ Approach,” Nano Letters, 24, 19, 5847-5854 (2024). https://doi.org/10.1021/acs.nanolett.4c01127

S. Ekatan, T. Xue, Z. Song, T. Yang, D. Ndaya, M. Shaw, J. Cheng and Y. Lin, “Thermomechanical Properties of Solid ‘Liquid Crystalline’ Films from Hot-Pressed Synthetic Polypeptides of Various Macromolecular Architectures,” Macromolecules, 57, 2008–2018 (2024). https://doi.org/10.1021/acs.macromol.3c02005

T. Yang, T. Xue, J. Mao, Y. Chen, H. Tian, A. Bartolome, H. Xia, X. Yao, C. V. Kumar, J. Cheng and Y. Lin, “Tailoring Synthetic Polypeptide Design for Directed Fibril Superstructure Formation and Enhanced Hydrogel Properties,” Journal of the American Chemical Society, 146, 9, 5823-5833 (2024). https://doi.org/10.1021/jacs.3c10762

W. Wang, H. Fu, Y. Lin, J. Cheng and Z. Song, “Cooperative Covalent Polymerization of N-carboxyanhydrides: from Kinetic Studies to Efficient Synthesis of Polypeptide Materials,” Accounts of Materials Research, 4, 604–615 (2023). https://doi.org/10.1021/accountsmr.3c00046

H. Duan, Z. Jia, M. Liaqat, M. D. Mellor, H. Tan, M. Nieh, Y. Lin, S. Link, C. F. Landes and J. He, “Site-Specific Chemistry on Gold Nanorods: Curvature-Guided Surface Dewetting and Supracolloidal Polymerization,” ACS Nano, 7, 12788–12797 (2023). https://doi.org/10.1021/acsnano.3c03929

J. Lu, Z. Xu, H. Fu, Y. Lin, H. Wang and H. Lu, “Room-Temperature Grafting from Synthesis of Protein-Polydisulfide Conjugates via Aggregation-Induced Polymerization,” Journal of the American Chemical Society, 144, 15709-15717 (2022). https://doi.org/10.1021/jacs.2c05997

H. Fu, R. Baumgartner, Z. Song, C. Chen, J. Cheng and Y. Lin, “Generalized Model of Cooperative Covalent Polymerization: Connecting the Supramolecular Binding Interactions with the Catalytic Behavior,” Macromolecules, 55, 2041-2050 (2022).  https://doi.org/10.1021/acs.macromol.1c02606

T. Yang, K. Benson, H. Fu, T. Xue, Z. Song, H. Duan, H. Xia, A. Kalluri, J. He, J. Cheng, C. Kumar and Y. Lin, “Modeling and Designing Particle-regulated Amyloid-like Assembly of Synthetic Polypeptides in Aqueous Solution,” Biomacromolecules, 23, 196–209 (2022). https://doi.org/10.1021/acs.biomac.1c01230

H. Duan, T. Malesky, J. Wang, C. Liu, H. Tan, M.P. Nieh, Y. Lin and J. He, “Patchy Metal Nanoparticles with Polymers: Controllable Growth and Two-Way Self-Assembly,” Nanoscale, 14, 7364-7371 (2022). https://doi.org/10.1039/D2NR01221A

H. Duan, C. Guan, J. Xue, T. Malesky, Y. Luo, Y. Lin, Y. Qin and J. He, “Facile synthesis of water-dispersible poly(3-hexylthiophene) nanoparticles with high yield and excellent colloidal stability,” iScience, 25, 104220 (2022). https://doi.org/10.1016/j.isci.2022.104220

H. Duan, Y. Lin and J. He, “Polymeric N-Heterocyclic Carbenes to Functionalize Plasmonic Metal Nanoparticles,” in World Scientific Reference on Plasmonic Nanomaterials Principles, Design and Bio-applications Vol. 3: Self-Assembly of Plasmonic Nanostructures, edited by Zhihong Nie, World Scientific Publishing (2022). https://doi.org/10.1142/12236-vol3

H. Duan, Y. Lin and J. He, “Metal Nanoparticles Grafted with Polymeric Ligands: Self-assembly Guided by Polymers in Solution,” in Encyclopedia of Nanomaterials, Elsevier (2021). https://doi.org/10.1016/B978-0-12-822425-0.00004-X